In vivo visualization of enantioselective targeting of amyloid and improvement of cognitive function by clickable chiral metallohelices

The pathogenesis of Alzheimer's disease (AD) is closely related to several contributing factors, especially amyloid-β (Aβ) aggregation. Bioorthogonal reactions provide a general, facile, and robust route for the localization and derivatization of Aβ-targeted agents. Herein, a pair of chiral alk...

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Detalles Bibliográficos
Autores principales: Du, Zhi, Liu, Chun, Liu, Zhenqi, Song, Hualong, Scott, Peter, Du, Xiubo, Ren, Jinsong, Qu, Xiaogang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847640/
https://www.ncbi.nlm.nih.gov/pubmed/36741518
http://dx.doi.org/10.1039/d2sc05897a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847640/
https://www.ncbi.nlm.nih.gov/pubmed/36741518
http://dx.doi.org/10.1039/d2sc05897a

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