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In vivo visualization of enantioselective targeting of amyloid and improvement of cognitive function by clickable chiral metallohelices
The pathogenesis of Alzheimer's disease (AD) is closely related to several contributing factors, especially amyloid-β (Aβ) aggregation. Bioorthogonal reactions provide a general, facile, and robust route for the localization and derivatization of Aβ-targeted agents. Herein, a pair of chiral alk...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847640/ https://www.ncbi.nlm.nih.gov/pubmed/36741518 http://dx.doi.org/10.1039/d2sc05897a |