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Nuclear accumulation of host transcripts during Zika Virus Infection

Zika virus (ZIKV) infects fetal neural progenitor cells (NPCs) causing severe neurodevelopmental disorders in utero. Multiple pathways involved in normal brain development are dysfunctional in infected NPCs but how ZIKV centrally reprograms these pathways remains unknown. Here we show that ZIKV infe...

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Detalles Bibliográficos
Autores principales: Leon, Kristoffer E., Khalid, Mir M., Flynn, Ryan A., Fontaine, Krystal A., Nguyen, Thong T., Kumar, G. Renuka, Simoneau, Camille R., Tomar, Sakshi, Jimenez-Morales, David, Dunlap, Mariah, Kaye, Julia, Shah, Priya S., Finkbeiner, Steven, Krogan, Nevan J., Bertozzi, Carolyn, Carette, Jan E., Ott, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847913/
https://www.ncbi.nlm.nih.gov/pubmed/36603024
http://dx.doi.org/10.1371/journal.ppat.1011070