Enantioselective inhibition of the SARS-CoV-2 main protease with rhenium(i) picolinic acid complexes

Infections of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have triggered a global pandemic with millions of deaths worldwide. Herein, the synthesis of functionalized Re(i) tricarbonyl complexes as inhibitors of the SARS-CoV-2 main protease, also referred to as the 3-chymotrypsin...

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Detalles Bibliográficos
Autores principales: Karges, Johannes, Giardini, Miriam A., Blacque, Olivier, Woodworth, Brendon, Siqueira-Neto, Jair L., Cohen, Seth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9848156/
https://www.ncbi.nlm.nih.gov/pubmed/36741526
http://dx.doi.org/10.1039/d2sc05473f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9848156/
https://www.ncbi.nlm.nih.gov/pubmed/36741526
http://dx.doi.org/10.1039/d2sc05473f

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