Discovery of coumaric acid derivatives hinted by coastal marine source to seek for uric acid lowering agents

In this work, a series of novel compounds Spartinin C1-C24 were screened, synthesised and evaluated for inhibiting xanthine oxidase thus lowering serum uric acid level. The backbones were derived from the components of coastal marine source Spartina alterniflora and marketed drugs. The top hits Spar...

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Detalles Bibliográficos
Autores principales: Yang, Yu-Shun, Wang, Bin, Liu, Junzhong, Li, Qin, Jiao, Qin-Cai, Qin, Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9848256/
https://www.ncbi.nlm.nih.gov/pubmed/36629443
http://dx.doi.org/10.1080/14756366.2022.2163241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9848256/
https://www.ncbi.nlm.nih.gov/pubmed/36629443
http://dx.doi.org/10.1080/14756366.2022.2163241

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