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Discovery of coumaric acid derivatives hinted by coastal marine source to seek for uric acid lowering agents
In this work, a series of novel compounds Spartinin C1-C24 were screened, synthesised and evaluated for inhibiting xanthine oxidase thus lowering serum uric acid level. The backbones were derived from the components of coastal marine source Spartina alterniflora and marketed drugs. The top hits Spar...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9848256/ https://www.ncbi.nlm.nih.gov/pubmed/36629443 http://dx.doi.org/10.1080/14756366.2022.2163241 |