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Identification of a new structural family of SGK1 inhibitors as potential neuroprotective agents
SGK1 is a serine/threonine kinase involved in several neurodegenerative-related pathways such as apoptosis, neuroinflammation, ionic channel regulation, and autophagy, among others. Despite its potential role as a pharmacological target against this kind of diseases, there are no reported inhibitors...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9848319/ https://www.ncbi.nlm.nih.gov/pubmed/36637025 http://dx.doi.org/10.1080/14756366.2022.2153841 |