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Identification of a new structural family of SGK1 inhibitors as potential neuroprotective agents

SGK1 is a serine/threonine kinase involved in several neurodegenerative-related pathways such as apoptosis, neuroinflammation, ionic channel regulation, and autophagy, among others. Despite its potential role as a pharmacological target against this kind of diseases, there are no reported inhibitors...

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Detalles Bibliográficos
Autores principales: Maestro, Ines, Madruga, Enrique, Boya, Patricia, Martínez, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9848319/
https://www.ncbi.nlm.nih.gov/pubmed/36637025
http://dx.doi.org/10.1080/14756366.2022.2153841

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