Design, synthesis, molecular modelling and antitumor evaluation of S-glucosylated rhodanines through topo II inhibition and DNA intercalation

In the present study, 5-arylidene rhodanine derivatives 3a–f, N-glucosylation rhodanine 6, S-glucosylation rhodanine 7, N-glucoside rhodanine 8 and S-glucosylation 5-arylidene rhodanines 13a–c were synthesised and screened for cytotoxicity against a panel of cancer cells with investigating the effec...

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Detalles Bibliográficos
Autores principales: Khodair, Ahmed I., Alzahrani, Fatimah M., Awad, Mohamed K., Al-Issa, Siham A., Al-Hazmi, Ghaferah H., Nafie, Mohamed S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9848385/
https://www.ncbi.nlm.nih.gov/pubmed/36629439
http://dx.doi.org/10.1080/14756366.2022.2163996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9848385/
https://www.ncbi.nlm.nih.gov/pubmed/36629439
http://dx.doi.org/10.1080/14756366.2022.2163996

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