Kindlin-2 inhibits TNF/NF-κB-Caspase 8 pathway in hepatocytes to maintain liver development and function

Inflammatory liver diseases are a major cause of morbidity and mortality worldwide; however, underlying mechanisms are incompletely understood. Here we show that deleting the focal adhesion protein Kindlin-2 expression in hepatocytes using the Alb-Cre transgenic mice causes a severe inflammation, re...

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Detalles Bibliográficos
Autores principales: Gao, Huanqing, Zhong, Yiming, Zhou, Liang, Lin, Sixiong, Hou, Xiaoting, Ding, Zhen, Li, Yan, Yao, Qing, Cao, Huiling, Zou, Xuenong, Chen, Di, Bai, Xiaochun, Xiao, Guozhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9848388/
https://www.ncbi.nlm.nih.gov/pubmed/36622102
http://dx.doi.org/10.7554/eLife.81792

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9848388/
https://www.ncbi.nlm.nih.gov/pubmed/36622102
http://dx.doi.org/10.7554/eLife.81792

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