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Optimized self-microemulsifying drug delivery system improves the oral bioavailability and brain delivery of coenzyme Q(10)
Our study aimed to develop a self-microemulsifying drug delivery system for the poorly aqueous-soluble drug Coenzyme Q(10), to improve the dissolution and the oral bioavailability. Excipients were selected based on their Coenzyme Q(10) solubility, and their concentrations were set for the optimizati...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9848412/ https://www.ncbi.nlm.nih.gov/pubmed/35850616 http://dx.doi.org/10.1080/10717544.2022.2100515 |