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Optimized self-microemulsifying drug delivery system improves the oral bioavailability and brain delivery of coenzyme Q(10)

Our study aimed to develop a self-microemulsifying drug delivery system for the poorly aqueous-soluble drug Coenzyme Q(10), to improve the dissolution and the oral bioavailability. Excipients were selected based on their Coenzyme Q(10) solubility, and their concentrations were set for the optimizati...

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Detalles Bibliográficos
Autores principales: Chhitij, Thapa, Seo, Jo-Eun, Keum, Taekwang, Noh, Gyubin, Bashyal, Santosh, Lamichhane, Shrawani, Kim, Jung Hwan, Lee, Jae Heon, Park, Jee Hun, Choi, Jaewoong, Song, Se Hyun, Lee, Sangkil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9848412/
https://www.ncbi.nlm.nih.gov/pubmed/35850616
http://dx.doi.org/10.1080/10717544.2022.2100515