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Hydroxypropyl chitosan nail lacquer of ciclopirox-PLGA nanocapsules for augmented in vitro nail plate absorption and onychomycosis treatment

Onychomycosis accounts for 90% of nail infections worldwide. Topical therapy provides localized effects with minimal adverse systemic actions, yet its effectiveness is limited by minimal drug permeation through the keratinized nail plate. Ciclopirox (CIX) is a FDA-approved broad-spectrum antimycotic...

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Detalles Bibliográficos
Autores principales: Gaballah, Eman Yahya, Borg, Thanaa Mohammed, Mohamed, Elham Abdelmonem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9848413/
https://www.ncbi.nlm.nih.gov/pubmed/36372978
http://dx.doi.org/10.1080/10717544.2022.2144543