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Development and optimization of amphiphilic self-assembly into nanostructured liquid crystals for transdermal delivery of an antidiabetic SGLT2 inhibitor

The anti-hyperglycemic sodium glucose co-transporter 2 inhibitor Canagliflozin (CFZ) represents a recent antihyperglycemic modality, yet it suffers from low oral bioavailability. The current work aims to formulate CFZ-loaded transdermal nanostructured liquid crystal gel matrix (NLCG) to improve its...

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Detalles Bibliográficos
Autores principales: Lotfy, Nancy M., Ahmed, Mohammed Abdallah, El Hoffy, Nada M., Bendas, Ehab R., Morsi, Nadia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9848419/
https://www.ncbi.nlm.nih.gov/pubmed/36377493
http://dx.doi.org/10.1080/10717544.2022.2144546