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The structure of DarB in complex with Rel(NTD) reveals nonribosomal activation of Rel stringent factors

Rel stringent factors are bifunctional ribosome-associated enzymes that catalyze both synthesis and hydrolysis of the alarmones (p)ppGpp. Besides the allosteric control by starved ribosomes and (p)ppGpp, Rel is regulated by various protein factors depending on specific stress conditions, including t...

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Detalles Bibliográficos
Autores principales: Ainelo, Andres, Caballero-Montes, Julien, Bulvas, Ondřej, Ernits, Karin, Coppieters ‘t Wallant, Kyo, Takada, Hiraku, Craig, Sophie Z., Mazzucchelli, Gabriel, Zedek, Safia, Pichová, Iva, Atkinson, Gemma C., Talavera, Ariel, Martens, Chloe, Hauryliuk, Vasili, Garcia-Pino, Abel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9848473/
https://www.ncbi.nlm.nih.gov/pubmed/36652515
http://dx.doi.org/10.1126/sciadv.ade4077