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P08 A Phase 1, randomized, double-blind study to evaluate the safety, tolerability, and immunogenicity of a 21-valent pneumococcal conjugate vaccine (PCV) (V116) in adults

BACKGROUND: V116, an investigational 21-valent PCV, contains the following pneumococcal polysaccharides (PnPs): 3, 6A, 7F, 8, 9N, 10A, 11A, 12F, 15A, 16F, 17F, 19A, 20, 22F, 23A, 23B, 24F, 31, 33F, 35B, and a de-O-acetylated 15B (deOAc15B). This phase 1 study evaluated the safety, tolerability, and...

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Detalles Bibliográficos
Autores principales: Platt, Heather, Fernsler, Doreen, Gallagher, Nancy, Sapre, Aditi, Polis, Adam, Hall, Lori, Tamms, Gretchen, Schwartz, Howard, Skinner, Julie, Joyce, Joseph, Murphy, Rocio, Musey, Luwy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9848842/
http://dx.doi.org/10.1093/jacamr/dlac133.012