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USP9X-mediated NRP1 deubiquitination promotes liver fibrosis by activating hepatic stellate cells

Liver fibrosis is a complex fibrotic process that develops early in the course of cirrhosis and is caused by chronic liver damage. The activation of hepatic stellate cells is primarily responsible for the fibrosis process. Studies show that NRP1 influences HSC motility and migration. However, whethe...

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Detalles Bibliográficos
Autores principales: Zhao, Jinqiu, Bai, Jie, Peng, Fengling, Qiu, Chan, Li, Yongguo, Zhong, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849111/
https://www.ncbi.nlm.nih.gov/pubmed/36653359
http://dx.doi.org/10.1038/s41419-022-05527-9