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Characterisation of AMB-FUBINACA metabolism and CB(1)-mediated activity of its acid metabolite

PURPOSE: AMB-FUBINACA is a synthetic cannabinoid receptor agonist (SCRA) which is primarily metabolised by hepatic enzymes producing AMB-FUBINACA carboxylic acid. The metabolising enzymes associated with this biotransformation remain unknown. This study aimed to determine if AMB-FUBINACA metabolism...

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Detalles Bibliográficos
Autores principales: Webb, Hunter D. J., Finlay, David B., Chen, Shuli, Vernall, Andrea J., Sparkes, Eric, Banister, Samuel D., Rosengren, Rhonda J., Glass, Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849163/
https://www.ncbi.nlm.nih.gov/pubmed/36652070
http://dx.doi.org/10.1007/s11419-022-00649-3