The germline factor DDX4 contributes to the chemoresistance of small cell lung cancer cells

Human cancers often re-express germline factors, yet their mechanistic role in oncogenesis and cancer progression remains unknown. Here we demonstrate that DEAD-box helicase 4 (DDX4), a germline factor and RNA helicase conserved in all multicellular organisms, contributes to increased cell motility...

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Detalles Bibliográficos
Autores principales: Noyes, Christopher, Kitajima, Shunsuke, Li, Fengkai, Suita, Yusuke, Miriyala, Saradha, Isaac, Shakson, Ahsan, Nagib, Knelson, Erik, Vajdi, Amir, Tani, Tetsuo, Thai, Tran C., Xu, Derek, Murai, Junko, Tapinos, Nikos, Takahashi, Chiaki, Barbie, David A., Yajima, Mamiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849207/
https://www.ncbi.nlm.nih.gov/pubmed/36653474
http://dx.doi.org/10.1038/s42003-023-04444-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849207/
https://www.ncbi.nlm.nih.gov/pubmed/36653474
http://dx.doi.org/10.1038/s42003-023-04444-7

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