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Revealing the tissue-level complexity of endogenous glucagon-like peptide-1 receptor expression and signaling

The glucagon-like peptide-1 receptor (GLP1R) is a class B G protein-coupled receptor (GPCR) involved in glucose homeostasis and food intake. GLP1R agonists (GLP1RA) are widely used in the treatment of diabetes and obesity, yet visualizing the endogenous localization, organization and dynamics of a G...

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Detalles Bibliográficos
Autores principales: Ast, Julia, Nasteska, Daniela, Fine, Nicholas H. F., Nieves, Daniel J., Koszegi, Zsombor, Lanoiselée, Yann, Cuozzo, Federica, Viloria, Katrina, Bacon, Andrea, Luu, Nguyet T., Newsome, Philip N., Calebiro, Davide, Owen, Dylan M., Broichhagen, Johannes, Hodson, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849236/
https://www.ncbi.nlm.nih.gov/pubmed/36653347
http://dx.doi.org/10.1038/s41467-022-35716-1