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Revealing the tissue-level complexity of endogenous glucagon-like peptide-1 receptor expression and signaling
The glucagon-like peptide-1 receptor (GLP1R) is a class B G protein-coupled receptor (GPCR) involved in glucose homeostasis and food intake. GLP1R agonists (GLP1RA) are widely used in the treatment of diabetes and obesity, yet visualizing the endogenous localization, organization and dynamics of a G...
Autores principales: | Ast, Julia, Nasteska, Daniela, Fine, Nicholas H. F., Nieves, Daniel J., Koszegi, Zsombor, Lanoiselée, Yann, Cuozzo, Federica, Viloria, Katrina, Bacon, Andrea, Luu, Nguyet T., Newsome, Philip N., Calebiro, Davide, Owen, Dylan M., Broichhagen, Johannes, Hodson, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849236/ https://www.ncbi.nlm.nih.gov/pubmed/36653347 http://dx.doi.org/10.1038/s41467-022-35716-1 |
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