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Mutant plasminogen in hereditary angioedema is bypassing FXII/kallikrein to generate bradykinin
Hereditary angioedema (HAE) is characterized by recurrent localized edema in various organs, which can be potentially fatal. There are different types of hereditary angioedema, which include genetic deficiency of C1 inhibitor (C1-INH) and hereditary angioedema with normal C1-INH (HAEnCI). In HAEnCI...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849239/ https://www.ncbi.nlm.nih.gov/pubmed/36685169 http://dx.doi.org/10.3389/fphys.2022.1090732 |