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Mutant plasminogen in hereditary angioedema is bypassing FXII/kallikrein to generate bradykinin

Hereditary angioedema (HAE) is characterized by recurrent localized edema in various organs, which can be potentially fatal. There are different types of hereditary angioedema, which include genetic deficiency of C1 inhibitor (C1-INH) and hereditary angioedema with normal C1-INH (HAEnCI). In HAEnCI...

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Detalles Bibliográficos
Autores principales: Hintze, Stefan, Möhl, Britta S., Beyerl, Jessica, Wulff, Karin, Wieser, Andreas, Bork, Konrad, Meinke, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849239/
https://www.ncbi.nlm.nih.gov/pubmed/36685169
http://dx.doi.org/10.3389/fphys.2022.1090732