Smarcd3 is an epigenetic modulator of the metabolic landscape in pancreatic ductal adenocarcinoma

Pancreatic cancer is characterized by extensive resistance to conventional therapies, making clinical management a challenge. Here we map the epigenetic dependencies of cancer stem cells, cells that preferentially evade therapy and drive progression, and identify SWI/SNF complex member SMARCD3 as a...

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Detalles Bibliográficos
Autores principales: Ferguson, L. Paige, Gatchalian, Jovylyn, McDermott, Matthew L., Nakamura, Mari, Chambers, Kendall, Rajbhandari, Nirakar, Lytle, Nikki K., Rosenthal, Sara Brin, Hamilton, Michael, Albini, Sonia, Wartenberg, Martin, Zlobec, Inti, Galván, José A., Karamitopoulou, Eva, Vavinskaya, Vera, Wascher, Alexis, Lowy, Andrew M., Schürch, Christian M., Puri, Pier Lorenzo, Bruneau, Benoit G., Hargreaves, Diana C., Reya, Tannishtha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849267/
https://www.ncbi.nlm.nih.gov/pubmed/36653361
http://dx.doi.org/10.1038/s41467-023-35796-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849267/
https://www.ncbi.nlm.nih.gov/pubmed/36653361
http://dx.doi.org/10.1038/s41467-023-35796-7

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