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Inefficient Batteries in Heart Failure: Metabolic Bottlenecks Disrupting the Mitochondrial Ecosystem

Mitochondrial abnormalities have long been described in the setting of cardiomyopathies and heart failure (HF), yet the mechanisms of mitochondrial dysfunction in cardiac pathophysiology remain poorly understood. Many studies have described HF as an energy-deprived state characterized by a decline i...

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Detalles Bibliográficos
Autores principales: Schwartz, Brian, Gjini, Petro, Gopal, Deepa M., Fetterman, Jessica L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849281/
https://www.ncbi.nlm.nih.gov/pubmed/36687274
http://dx.doi.org/10.1016/j.jacbts.2022.03.017