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Protein Expression of Amino Acid Transporters Is Altered in Isolated Cerebral Microvessels of 5xFAD Mouse Model of Alzheimer’s Disease

Membrane transporters such as ATP-binding cassette (ABC) and solute carrier (SLC) transporters expressed at the neurovascular unit (NVU) play an important role in drug delivery to the brain and have been demonstrated to be involved in Alzheimer’s disease (AD) pathogenesis. However, our knowledge of...

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Detalles Bibliográficos
Autores principales: Puris, Elena, Saveleva, Liudmila, de Sousa Maciel, Izaque, Kanninen, Katja M., Auriola, Seppo, Fricker, Gert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849299/
https://www.ncbi.nlm.nih.gov/pubmed/36367657
http://dx.doi.org/10.1007/s12035-022-03111-y