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Detection of antibodies against the huntingtin protein in human plasma

Huntington’s disease (HD) is a dominantly inherited neurodegenerative disorder resulting from a CAG expansion in the huntingtin (HTT) gene, which leads to the production and accumulation of mutant huntingtin (mHTT). While primarily considered a disorder of the central nervous system, multiple change...

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Detalles Bibliográficos
Autores principales: Denis, Hélèna L., Alpaugh, Melanie, Alvarez, Claudia P., Fenyi, Alexis, Barker, Roger A., Chouinard, Sylvain, Arrowsmith, Cheryl H., Melki, Ronald, Labib, Richard, Harding, Rachel J., Cicchetti, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849309/
https://www.ncbi.nlm.nih.gov/pubmed/36651994
http://dx.doi.org/10.1007/s00018-023-04687-x