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Position-dependent effects of RNA-binding proteins in the context of co-transcriptional splicing

Alternative splicing is an important step in eukaryotic mRNA pre-processing which increases the complexity of gene expression programs, but is frequently altered in disease. Previous work on the regulation of alternative splicing has demonstrated that splicing is controlled by RNA-binding proteins (...

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Detalles Bibliográficos
Autores principales: Horn, Timur, Gosliga, Alison, Li, Congxin, Enculescu, Mihaela, Legewie, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849329/
https://www.ncbi.nlm.nih.gov/pubmed/36653378
http://dx.doi.org/10.1038/s41540-022-00264-3