SIRT6 is a key regulator of mitochondrial function in the brain

The SIRT6 deacetylase has been implicated in DNA repair, telomere maintenance, glucose and lipid metabolism and, importantly, it has critical roles in the brain ranging from its development to neurodegeneration. Here, we combined transcriptomics and metabolomics approaches to characterize the functi...

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Detalles Bibliográficos
Autores principales: Smirnov, Dmitrii, Eremenko, Ekaterina, Stein, Daniel, Kaluski, Shai, Jasinska, Weronika, Cosentino, Claudia, Martinez-Pastor, Barbara, Brotman, Yariv, Mostoslavsky, Raul, Khrameeva, Ekaterina, Toiber, Debra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849342/
https://www.ncbi.nlm.nih.gov/pubmed/36653345
http://dx.doi.org/10.1038/s41419-022-05542-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849342/
https://www.ncbi.nlm.nih.gov/pubmed/36653345
http://dx.doi.org/10.1038/s41419-022-05542-w

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