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SIRT6 is a key regulator of mitochondrial function in the brain
The SIRT6 deacetylase has been implicated in DNA repair, telomere maintenance, glucose and lipid metabolism and, importantly, it has critical roles in the brain ranging from its development to neurodegeneration. Here, we combined transcriptomics and metabolomics approaches to characterize the functi...
Autores principales: | Smirnov, Dmitrii, Eremenko, Ekaterina, Stein, Daniel, Kaluski, Shai, Jasinska, Weronika, Cosentino, Claudia, Martinez-Pastor, Barbara, Brotman, Yariv, Mostoslavsky, Raul, Khrameeva, Ekaterina, Toiber, Debra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849342/ https://www.ncbi.nlm.nih.gov/pubmed/36653345 http://dx.doi.org/10.1038/s41419-022-05542-w |
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