FAT1 expression in T-cell acute lymphoblastic leukemia (T-ALL) modulates proliferation and WNT signaling

FAT atypical cadherin 1 (FAT1), a transmembrane protein, is frequently mutated in various cancer types and has been described as context-dependent tumor suppressor or oncogene. The FAT1 gene is mutated in 12–16% of T-cell acute leukemia (T-ALL) and aberrantly expressed in about 54% of T-ALL cases co...

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Detalles Bibliográficos
Autores principales: Liebig, Sven, Neumann, Martin, Silva, Patricia, Ortiz-Tanchez, Jutta, Schulze, Veronika, Isaakidis, Konstandina, Schlee, Cornelia, Schroeder, Michael P., Beder, Thomas, Morris, Luc G. T., Chan, Timothy A., Bastian, Lorenz, Burmeister, Thomas, Schwartz, Stefan, Gökbuget, Nicola, Mochmann, Liliana H., Baldus, Claudia D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849452/
https://www.ncbi.nlm.nih.gov/pubmed/36653435
http://dx.doi.org/10.1038/s41598-023-27792-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849452/
https://www.ncbi.nlm.nih.gov/pubmed/36653435
http://dx.doi.org/10.1038/s41598-023-27792-0

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