NK- and T-cell granzyme B and K expression correlates with age, CMV infection and influenza vaccine-induced antibody titres in older adults

Granzymes are a family of serine-proteases that act as critical mediators in the cytolytic and immunomodulatory activities of immune cells such as CD8(+) T-cells and natural killer (NK) cells. Previous work indicates that both granzyme B (GZB) and K (GZK) are increased with age in CD8(+) T-cells, an...

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Detalles Bibliográficos
Autores principales: Verschoor, Chris P., Picard, Emilie, Andrew, Melissa K., Haynes, Laura, Loeb, Mark, Pawelec, Graham, Kuchel, George A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Aging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849551/
https://www.ncbi.nlm.nih.gov/pubmed/36685324
http://dx.doi.org/10.3389/fragi.2022.1098200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849551/
https://www.ncbi.nlm.nih.gov/pubmed/36685324
http://dx.doi.org/10.3389/fragi.2022.1098200

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