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Pre-existing Toxoplasma gondii infection increases susceptibility to pentylenetetrazol-induced seizures independent of traumatic brain injury in mice

INTRODUCTION: Post-traumatic epilepsy (PTE) is a debilitating chronic outcome of traumatic brain injury (TBI), and neuroinflammation is implicated in increased seizure susceptibility and epileptogenesis. However, how common clinical factors, such as infection, may modify neuroinflammation and PTE de...

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Detalles Bibliográficos
Autores principales: Baker, Tamara L., Uboldi, Alessandro D., Tonkin, Christopher J., Wright, David K., Vo, Anh, Wilson, Trevor, Mychasiuk, Richelle, McDonald, Stuart J., Semple, Bridgette D., Sun, Mujun, Shultz, Sandy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849700/
https://www.ncbi.nlm.nih.gov/pubmed/36683847
http://dx.doi.org/10.3389/fnmol.2022.1079097