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Caloric restriction delays age-related muscle atrophy by inhibiting 11β−HSD1 to promote the differentiation of muscle stem cells

INTRODUCTION: Calorie restriction (CR) is an important direction for the delay of sarcopenia in elderly individuals. However, the specific mechanisms of CR against aging are still unclear. METHODS: In this study, we used a CR model of elderly mice with muscle-specific 11β-hydroxysteroid dehydrogenas...

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Detalles Bibliográficos
Autores principales: Lv, Shan, Shen, Qianjin, Li, Hengzhen, Chen, Qun, Xie, Wenqing, Li, Yusheng, Wang, Xiaodong, Ding, Guoxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849809/
https://www.ncbi.nlm.nih.gov/pubmed/36687405
http://dx.doi.org/10.3389/fmed.2022.1027055