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NEDD4 attenuates oxidized low‑density lipoprotein‑induced inflammation and dysfunction in vascular endothelial cells via regulating APEX1 expression

Atherosclerosis chiefly results from inflammation as well as vascular endothelial cell dysfunction. Methylation levels of neuronally expressed developmentally downregulated 4 (NEDD4) were found to be fortified in atherosclerosis patients and NEDD4 deficiency enhanced vascular calcification. However,...

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Detalles Bibliográficos
Autores principales: Xu, Huiyu, Tan, Lijuan, Qu, Qiaofang, Zhang, Wutang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849851/
https://www.ncbi.nlm.nih.gov/pubmed/36684652
http://dx.doi.org/10.3892/etm.2023.11787