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The role played by ailanthone in inhibiting bone metastasis of breast cancer by regulating tumor-bone microenvironment through the RANKL-dependent pathway

Introduction: Bone metastasis of breast cancer (BC) is a process in which the disruption of the bone homeostatic microenvironment leads to an increase in osteoclast differentiation. Ailanthus altissima shows an inhibitory effect on osteoclast differentiation. Ailanthone (AIL) refers to a natural com...

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Detalles Bibliográficos
Autores principales: Wang, Yajun, Zhong, Zeyuan, Ma, Miao, Zhao, Yannan, Zhang, Chongjing, Qian, Zhi, Wang, Biyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849906/
https://www.ncbi.nlm.nih.gov/pubmed/36686653
http://dx.doi.org/10.3389/fphar.2022.1081978