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A high interferon gamma signature of CD8(+) T cells predicts response to neoadjuvant immunotherapy plus chemotherapy in gastric cancer

BACKGROUND: While the tumor microenvironment (TME) affects immune checkpoint blockade (ICB) efficacy, ICB also reshapes the characteristics of TME. Thus far, studies have focused on the TME evolution during neoadjuvant or adjuvant ICB therapy in gastric cancer (GC). However, the interaction between...

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Detalles Bibliográficos
Autores principales: Li, Sen, Li, Ke, Tian, Fei, Li, Hongle, Xia, Qingxin, Li, Tiepeng, Dong, Bing, Li, Danyang, Yu, Juan, Zhang, Junli, Wang, Li, Zhang, Chengjuan, Xu, Shuning, Zhao, Yuzhou, Liu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849934/
https://www.ncbi.nlm.nih.gov/pubmed/36685525
http://dx.doi.org/10.3389/fimmu.2022.1056144