PD-1 blocking strategy for enhancing the anti-tumor effect of CAR T cells targeted CD105

PURPOS: CD105 has become a promising target of immunotherapy development for highly specific expression on the neovascular surface of most types of tumor cells. In previous studies, we constructed a CAR T cell (CD105 CAR T cell) and observed significant antitumor activity. In this study, we optimize...

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Detalles Bibliográficos
Autores principales: Wang, Xi, Lai, Zhiheng, Pang, Yanyang, Sun, Qinghui, Yang, Wenli, Wang, Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849980/
https://www.ncbi.nlm.nih.gov/pubmed/36685461
http://dx.doi.org/10.1016/j.heliyon.2022.e12688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849980/
https://www.ncbi.nlm.nih.gov/pubmed/36685461
http://dx.doi.org/10.1016/j.heliyon.2022.e12688

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