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PD-1 blocking strategy for enhancing the anti-tumor effect of CAR T cells targeted CD105
PURPOS: CD105 has become a promising target of immunotherapy development for highly specific expression on the neovascular surface of most types of tumor cells. In previous studies, we constructed a CAR T cell (CD105 CAR T cell) and observed significant antitumor activity. In this study, we optimize...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849980/ https://www.ncbi.nlm.nih.gov/pubmed/36685461 http://dx.doi.org/10.1016/j.heliyon.2022.e12688 |