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Longitudinal changes in (18)F-Flutemetamol amyloid load in cognitively intact APOE4 carriers versus noncarriers: Methodological considerations

PURPOSE: Measuring longitudinal changes in amyloid load in the asymptomatic stage of Alzheimer’s disease is of high relevance for clinical research and progress towards more efficacious, timely treatments. Apolipoprotein E ε4 (APOE4) has a well-established effect on the rate of amyloid accumulation....

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Detalles Bibliográficos
Autores principales: Luckett, Emma S., Schaeverbeke, Jolien, De Meyer, Steffi, Adamczuk, Katarzyna, Van Laere, Koen, Dupont, Patrick, Vandenberghe, Rik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850036/
https://www.ncbi.nlm.nih.gov/pubmed/36621019
http://dx.doi.org/10.1016/j.nicl.2023.103321