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Cross-species high-resolution transcriptome profiling suggests biomarkers and therapeutic targets for ulcerative colitis

Background: Ulcerative colitis (UC) is a disorder with unknown etiology, and animal models play an essential role in studying its molecular pathophysiology. Here, we aim to identify common conserved pathological UC-related gene expression signatures between humans and mice that can be used as treatm...

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Detalles Bibliográficos
Autores principales: Yarani, Reza, Palasca, Oana, Doncheva, Nadezhda T., Anthon, Christian, Pilecki, Bartosz, Svane, Cecilie A. S., Mirza, Aashiq H., Litman, Thomas, Holmskov, Uffe, Bang-Berthelsen, Claus H., Vilien, Mogens, Jensen, Lars J., Gorodkin, Jan, Pociot, Flemming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850088/
https://www.ncbi.nlm.nih.gov/pubmed/36685283
http://dx.doi.org/10.3389/fmolb.2022.1081176