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Gradient differences of immunotherapy efficacy in metastatic melanoma related to sunlight exposure pattern: A population-based study

BACKGROUND: Immune checkpoint inhibitors (ICIs) have revolutionized metastatic melanoma (MM) treatment in just a few years. Ultraviolet (UV) in sunlight is the most significant environmental cause of melanoma, which is considered to be the main reason for tumor mutation burden (TMB) increase in mela...

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Detalles Bibliográficos
Autores principales: Liu, Mengsong, Li, Wenyuan, Ma, Xiao, Che, Yuhui, Wei, Bo, Chen, Mulan, Zhong, Lin, Zhao, Siqi, Chen, Anjing, Pang, Yaobin, Zeng, Jinhao, Guo, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850161/
https://www.ncbi.nlm.nih.gov/pubmed/36686834
http://dx.doi.org/10.3389/fonc.2022.1086664