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End-to-end approach for the characterization and control of product-related impurities in T cell bispecific antibody preparations

Antibody-based T cell-activating biologics are promising therapeutic medicines being developed for a number of indications, mainly in the oncology field. Among those, T cell bispecific antibodies are designed to bind one tumor-specific antigen and the T cell receptor at the same time, leading to a r...

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Detalles Bibliográficos
Autores principales: Larivière, Laurent, Krüger, Julia Eva, von Hirschheydt, Thomas, Schlothauer, Tilman, Bray-French, Katharine, Bader, Martin, Runza, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850176/
https://www.ncbi.nlm.nih.gov/pubmed/36687375
http://dx.doi.org/10.1016/j.ijpx.2023.100157