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End-to-end approach for the characterization and control of product-related impurities in T cell bispecific antibody preparations
Antibody-based T cell-activating biologics are promising therapeutic medicines being developed for a number of indications, mainly in the oncology field. Among those, T cell bispecific antibodies are designed to bind one tumor-specific antigen and the T cell receptor at the same time, leading to a r...
Autores principales: | Larivière, Laurent, Krüger, Julia Eva, von Hirschheydt, Thomas, Schlothauer, Tilman, Bray-French, Katharine, Bader, Martin, Runza, Valeria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850176/ https://www.ncbi.nlm.nih.gov/pubmed/36687375 http://dx.doi.org/10.1016/j.ijpx.2023.100157 |
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