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Drop-on-powder 3D printing of amorphous high dose oral dosage forms: Process development, opportunities and printing limitations

Drop-on-powder 3D printing is able to produce highly drug loaded solid oral dosage forms. However, this technique is mainly limited to well soluble drugs. The majority of pipeline compounds is poorly soluble, though, and requires solubility enhancement, e.g., via formation of amorphous solid dispers...

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Detalles Bibliográficos
Autores principales: Gottschalk, Nadine, Burkard, Alicia, Quodbach, Julian, Bogdahn, Malte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850179/
https://www.ncbi.nlm.nih.gov/pubmed/36687376
http://dx.doi.org/10.1016/j.ijpx.2022.100151