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Drop-on-powder 3D printing of amorphous high dose oral dosage forms: Process development, opportunities and printing limitations
Drop-on-powder 3D printing is able to produce highly drug loaded solid oral dosage forms. However, this technique is mainly limited to well soluble drugs. The majority of pipeline compounds is poorly soluble, though, and requires solubility enhancement, e.g., via formation of amorphous solid dispers...
Autores principales: | Gottschalk, Nadine, Burkard, Alicia, Quodbach, Julian, Bogdahn, Malte |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850179/ https://www.ncbi.nlm.nih.gov/pubmed/36687376 http://dx.doi.org/10.1016/j.ijpx.2022.100151 |
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