A network-guided protocol to discover susceptibility genes in genome-wide association studies using stability selection

We present a network-based protocol to discover susceptibility genes in case-control genome-wide association studies (GWASs). In short, this protocol looks for biomarkers that are informative of disease status and interconnected in an underlying biological network. This boosts discovery and interpre...

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Detalles Bibliográficos
Autores principales: Climente-González, Héctor, Azencott, Chloé-Agathe, Yamada, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850185/
https://www.ncbi.nlm.nih.gov/pubmed/36609152
http://dx.doi.org/10.1016/j.xpro.2022.101998

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850185/
https://www.ncbi.nlm.nih.gov/pubmed/36609152
http://dx.doi.org/10.1016/j.xpro.2022.101998

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