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A network-guided protocol to discover susceptibility genes in genome-wide association studies using stability selection
We present a network-based protocol to discover susceptibility genes in case-control genome-wide association studies (GWASs). In short, this protocol looks for biomarkers that are informative of disease status and interconnected in an underlying biological network. This boosts discovery and interpre...
Autores principales: | Climente-González, Héctor, Azencott, Chloé-Agathe, Yamada, Makoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850185/ https://www.ncbi.nlm.nih.gov/pubmed/36609152 http://dx.doi.org/10.1016/j.xpro.2022.101998 |
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