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EBV LMP1-C terminal binding affibody molecule downregulates MEK/ERK/p90RSK pathway and inhibits the proliferation of nasopharyngeal carcinoma cells in mouse tumor xenograft models

Nasopharyngeal carcinoma (NPC), is an Epstein-Barr virus (EBV) associated malignancy most common in Southern China and Southeast Asia. In southern China, it is one of the major causes of cancer-related death. Despite improvement in radiotherapy and chemotherapy techniques, locoregional recurrence an...

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Detalles Bibliográficos
Autores principales: Guo, Yanru, Kamara, Saidu, Zhang, Jing, Wen, He, Zheng, Maolin, Liu, Ying, Zhou, Luqi, Chen, Jun, Zhu, Shanli, Zhang, Lifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850235/
https://www.ncbi.nlm.nih.gov/pubmed/36683690
http://dx.doi.org/10.3389/fcimb.2022.1078504