Predicting protein stability changes upon mutation using a simple orientational potential

MOTIVATION: Structure-based stability prediction upon mutation is crucial for protein engineering and design, and for understanding genetic diseases or drug resistance events. For this task, we adopted a simple residue-based orientational potential that considers only three backbone atoms, previousl...

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Detalles Bibliográficos
Autores principales: Hernández, Iván Martín, Dehouck, Yves, Bastolla, Ugo, López-Blanco, José Ramón, Chacón, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850275/
https://www.ncbi.nlm.nih.gov/pubmed/36629451
http://dx.doi.org/10.1093/bioinformatics/btad011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850275/
https://www.ncbi.nlm.nih.gov/pubmed/36629451
http://dx.doi.org/10.1093/bioinformatics/btad011

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