Cargando…

Click-designed vanilloid-triazole conjugates as dual inhibitors of AChE and Aβ aggregation

Based on their reported neuroprotective properties, vanilloids provide a good starting point for the synthesis of anti-Alzheimer's disease (AD) agents. In this context, nine new 1,2,3-triazole conjugates of vanilloids were synthesized via click chemistry. The compounds were tested for their eff...

Descripción completa

Detalles Bibliográficos
Autores principales: Elsbaey, Marwa, Igarashi, Yasuhiro, Ibrahim, Mahmoud A. A., Elattar, Eman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850456/
https://www.ncbi.nlm.nih.gov/pubmed/36756452
http://dx.doi.org/10.1039/d2ra07539c